EFHD2
Function
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Tissue Specificity
Found in lymphocytes; preferentially expressed in CD8+ cells.
Cellular localization
- Membrane raft
- In a mouse immature B-cell line WEHI-231.
Alternative names
SWS1, EFHD2, EF-hand domain-containing protein D2, Swiprosin-1