EHBP1L1
Domain
The CAAX motif is a signal for prenylation and required for endosomal colocalization with Rab8 and Rab10.
The bivalent Mical/EHBP Rab binding (bMERB) domain, mediates binding to Rab8, Rab10, Rab10, Rab13 and Rab15 (in their GTP-bound forms).
Function
May act as Rab effector protein and play a role in vesicle trafficking.
Post-translational modifications
Prenylated (Probable). Farnelysation (predominant) and geranylgeranylation has been observed in vitro.
Cellular localization
- Endosome
Alternative names
EH domain-binding protein 1-like protein 1, EHBP1L1