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EHD4

Domain

The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.

Function

ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport.

Sequence Similarities

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.

Tissue Specificity

Highly expressed in pancreas and heart.

Cellular localization

Alternative names

HCA10, HCA11, PAST4, FKSG7, EHD4, EH domain-containing protein 4, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4

swissprot:Q9H223 omim:605892 entrezGene:30844