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Domain

The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.

Function

ATP- and membrane-binding protein that probably controls membrane reorganization/tubulation upon ATP hydrolysis. Plays a role in early endosomal transport.

Sequence similarities

Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. EHD subfamily.

Tissue specificity

Highly expressed in pancreas and heart.

Cellular localization

  • Early endosome membrane
  • Peripheral membrane protein
  • Cytoplasmic side
  • Recycling endosome membrane
  • Peripheral membrane protein
  • Cytoplasmic side
  • Cell membrane
  • Peripheral membrane protein
  • Cytoplasmic side

Alternative names

HCA10, HCA11, PAST4, FKSG7, EHD4, EH domain-containing protein 4, Hepatocellular carcinoma-associated protein 10/11, PAST homolog 4

Target type

Proteins

Molecular weight

61175Da

We found 1 product in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'EHD4' (1)

Products