ELAPOR1
Function
May protect cells from cell death by inducing cytosolic vacuolization and up-regulating the autophagy pathway (PubMed:21072319). May play a role in apoptosis and cell proliferation through its interaction with HSPA5 (PubMed:26045166).
Sequence Similarities
Belongs to the ELAPOR family.
Tissue Specificity
Expressed in normal endometrium but overexpressed in endometroid tumors.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Late endosome membrane
- Single-pass type I membrane protein
- Golgi apparatus
- trans-Golgi network membrane
- Single-pass type I membrane protein
- Lysosome membrane
- Single-pass membrane protein
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
Alternative names
EIG121, KIAA1324, UNQ2426/PRO4985, ELAPOR1, Endosome/lysosome-associated apoptosis and autophagy regulator 1, Estrogen-induced gene 121 protein