EMCN

Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.

Highly O-glycosylated. Sialic acid-rich glycoprotein.

Expressed in heart, kidney and lung.

• Isoform 1
• Cell membrane
• Single-pass type I membrane protein
• Membrane
• Single-pass type I membrane protein
• Consistently localized to the plasma membrane and less abundantly to Golgi-like perinuclear stacks.
• Isoform 2
• Secreted

EMCN2, MUC14, EMCN, Endomucin, Endomucin-2, Gastric cancer antigen Ga34, Mucin-14, MUC-14

• entrezGene:51705
• omim:608350
• swissprot:Q9ULC0

Proteins

Developmental Biology

27452Da