Endothelial cell-specific molecule 1
Function
Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions.
Post-translational modifications
May contain intrachain disulfide bonds.
O-glycosylated; contains chondroitin sulfate and dermatan sulfate.
Tissue Specificity
Expressed in lung, on the vascular capillary network within alveolar walls, and also at lower level in kidney.
Cellular localization
- Secreted
Alternative names
Endothelial cell-specific molecule 1, ESM-1, ESM1