ENGASE
Function
Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol.
Sequence Similarities
Belongs to the glycosyl hydrolase 85 family.
Tissue Specificity
Widely expressed. Expressed at higher level in thymus and spleen.
Cellular localization
- Cytoplasm
- Cytosol
Alternative names
Cytosolic endo-beta-N-acetylglucosaminidase, ENGase, ENGASE