ENKUR

Domain

The IQ motif is involved in calmodulin binding.

Function

Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel (By similarity). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189).

Tissue Specificity

Expressed in airway epithelial cells.

Cellular localization

• Cytoplasm
• Cytoskeleton
• Cilium axoneme
• Cytoplasm
• Cytoskeleton
• Flagellum axoneme
• Sperm acrosomal crescent and flagellar principal piece.

Alternative names

C10orf63, ENKUR, Enkurin

Database links

swissprot:Q8TC29 entrezGene:219670 genbank:NM_145010 omim:611025