Epsin 2

The NPF repeat domain is involved in EPS15 binding.

The DPW repeat domain is involved in AP-2 and clathrin binding.

Plays a role in the formation of clathrin-coated invaginations and endocytosis.

Ubiquitinated.

Belongs to the epsin family.

Highest expression is found in brain. Detected at lower levels in lung and liver.

• Cytoplasm
• Cytoplasmic vesicle
• Clathrin-coated vesicle
• In punctate structures throughout the cell, associated with clathrin-coated vesicles, and particularly concentrated in the region of the Golgi complex.

KIAA1065, EPN2, Epsin-2, EPS-15-interacting protein 2

• entrezGene:22905
• omim:607263
• swissprot:O95208

Proteins

Oncology

68482Da