EPYC
Function
May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization.
Post-translational modifications
The O-linked polysaccharides on Thr-60 and Ser-96 are probably the mucin type linked to GalNAc. There is one glycosaminoglycan chain, known to be dermatan sulfate, and it is probably the O-glycosylation at Ser-64.
Sequence Similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
Tissue Specificity
Cartilage, ligament, and placenta.
Cellular localization
- Secreted
- Extracellular space
- Extracellular matrix
Alternative names
DSPG3, PGLB, SLRR3B, EPYC, Epiphycan, Dermatan sulfate proteoglycan 3, Proteoglycan-Lb, Small chondroitin/dermatan sulfate proteoglycan, PG-Lb