ESAT6

A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm.

Belongs to the WXG100 family. ESAT-6 subfamily.

• Secreted
• Host membrane
• Probably secreted via the ESX-1 / type VII secretion system (T7SS). A central pair of alpha helices probably insert into host membrane.

esaT6, MT3989, esxA, 6 kDa early secretory antigenic target, ESAT-6

• swissprot:P9WNK6

Proteins

9904Da