eutC
Domain
Partial trypsin digestion of this subunit (removing the first 28 residues) yields an active protein less susceptible to aggregation.
Function
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds (PubMed:19762342). Ethanolamine ammonia-lyase (EAL) allows bacteria to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12. It is spontaneously inactivated by its substrate and reactivated by EutA (PubMed:15466038). Directly targeted to the BMC. May play a role in bacterial microcompartment (BMC) assembly or maintenance (By similarity).
Pathway
Amine and polyamine degradation; ethanolamine degradation.
Sequence Similarities
Belongs to the EutC family.
Cellular localization
- Bacterial microcompartment
Alternative names
b2440, JW2433, eutC, Ethanolamine ammonia-lyase small subunit, EAL small subunit, Ethanolamine ammonia-lyase beta subunit, Ethanolamine ammonia-lyase light chain, Ethanolamine deaminase small subunit