EVPL
Function
Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments.
Sequence Similarities
Belongs to the plakin or cytolinker family.
Tissue Specificity
Exclusively expressed in stratified squamous epithelia.
Cellular localization
- Cell junction
- Desmosome
- Cornified envelope
- Cytoplasm
- Cytoskeleton
- Colocalized with DSP at desmosomes and along intermediate filaments.
Alternative names
Envoplakin, 210 kDa cornified envelope precursor protein, 210 kDa paraneoplastic pemphigus antigen, p210, EVPL