EXOC3
Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Sequence Similarities
Belongs to the SEC6 family.
Tissue Specificity
Expressed in epididymis (at protein level).
Cellular localization
- Cytoplasm
- Cytoplasm
- Perinuclear region
- Cell projection
- Growth cone
- Midbody
- Golgi apparatus
- Cell projection
- Neuron projection
- Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
Alternative names
SEC6, SEC6L1, EXOC3, Exocyst complex component 3, Exocyst complex component Sec6