Sec8

Function

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

Sequence similarities

Belongs to the SEC8 family.

Cellular localization

• Midbody
• Midbody ring
• Cell projection
• Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). Localizes at the leading edge of migrating cells (By similarity).

Alternative names

• Exocyst complex component 4
• Exocyst complex component Sec8
• SEC8L1
• SEC8
• KIAA1699
• EXOC4

Database links

• entrezGene:60412
• omim:608185
• swissprot:Q96A65

Target type

Proteins

Molecular weight

110498Da