FAAP100
Function
Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
Cellular localization
- Nucleus
Alternative names
C17orf70, FAAP100, Fanconi anemia core complex-associated protein 100, Fanconi anemia-associated protein of 100 kDa