FABP1

Domain

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

Function

Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).

Sequence similarities

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Cellular localization

• Cytoplasm

Alternative names

• Fatty acid-binding protein 1
• Liver-type fatty acid-binding protein
• L-FABP
• FABP1
• FABPL

Database links

• entrezGene:2168
• omim:134650
• swissprot:P07148

Target type

Proteins

Molecular weight

14208Da