Fabp1
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Function
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
Sequence Similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Cellular localization
- Cytoplasm
Alternative names
Fabpl, Fabp1, 14 kDa selenium-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP