FABP7
Domain
Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
Function
B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).
Sequence Similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Tissue Specificity
Expressed in brain and other neural tissues.
Cellular localization
- Cytoplasm
Alternative names
BLBP, FABPB, MRG, FABP7, Brain lipid-binding protein, Brain-type fatty acid-binding protein, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, B-FABP