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FANK1

Domain

The fibronectin type-III domain mediates interaction with COPS5 and RYBP.

Function

Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis.

Post-translational modifications

Polyubiquitinated. Polyubiquitination leads to proteasomal degradation.

Tissue Specificity

Mostly restricted to testis.

Cellular localization

Alternative names

HSD13, UNQ6504/PRO21382, FANK1, Fibronectin type 3 and ankyrin repeat domains protein 1

swissprot:Q8TC84 omim:611640 entrezGene:92565