CD89

Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.

Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages; however only one isoform is expressed at alveolar macrophages surfaces.

• Isoform A.1
• Cell membrane
• Single-pass type I membrane protein
• Isoform A.2
• Cell membrane
• Single-pass type I membrane protein
• Isoform A.3
• Cell membrane
• Single-pass type I membrane protein
• Isoform B
• Secreted
• Isoform B-delta-S2
• Secreted

CD89, FCAR, Immunoglobulin alpha Fc receptor, IgA Fc receptor

• entrezGene:2204
• omim:147045
• swissprot:P24071

Proteins

Immunology & Infectious Disease

32265Da