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FEZF2

Function

Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large layer V pyramidal neurons. May be involved in innate immunity (By similarity).

Sequence Similarities

Belongs to the krueppel C2H2-type zinc-finger protein family.

Cellular localization

Alternative names

FEZL, ZNF312, FKSG36, FEZF2, Fez family zinc finger protein 2, Forebrain embryonic zinc finger-like protein 2, Zinc finger protein 312, Zinc finger protein Fez-like

swissprot:Q8TBJ5 omim:607414 entrezGene:55079