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Function

Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development.

Involvement in disease

Deafness with labyrinthine aplasia, microtia and microdontia

LAMM

Unique autosomal recessive syndrome characterized by type I microtia, microdontia, and profound congenital deafness associated with a complete absence of inner ear structures (Michel aplasia).

None

The disease is caused by variants affecting the gene represented in this entry.

Sequence similarities

Belongs to the heparin-binding growth factors family.

Cellular localization

  • Secreted

Alternative names

INT2, FGF3, Fibroblast growth factor 3, FGF-3, Heparin-binding growth factor 3, Proto-oncogene Int-2, HBGF-3

Target type

Proteins

Primary research area

Oncology

Molecular weight

26887Da

We found 2 products in 2 categories

Primary Antibodies

Target

Application

Reactive species

Assay Kits

Target

Reactive species

Detection method

Search our catalogue for 'FGF3' (2)

Products