FGF4
Function
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. May play a role in embryonic molar tooth bud development via inducing the expression of MSX1, MSX2 and MSX1-mediated expression of SDC1 in dental mesenchyme cells (By similarity).
Sequence Similarities
Belongs to the heparin-binding growth factors family.
Cellular localization
- Secreted
Alternative names
HST, HSTF1, KS3, FGF4, Fibroblast growth factor 4, FGF-4, Heparin secretory-transforming protein 1, Heparin-binding growth factor 4, Transforming protein KS3, HST-1, HSTF-1, HBGF-4