FKBP3
Function
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
Sequence Similarities
Belongs to the FKBP-type PPIase family.
Cellular localization
- Nucleus
Alternative names
FKBP25, FKBP3, Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, FK506-binding protein 3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase, 25 kDa FKBP, FKBP-25, FKBP-3