Flotillin 1

Function

May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.

Sequence similarities

Belongs to the band 7/mec-2 family. Flotillin subfamily.

Cellular localization

• Cell membrane
• Peripheral membrane protein
• Endosome
• Membrane
• Caveola
• Peripheral membrane protein
• Melanosome
• Membrane raft
• Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Membrane-associated protein of caveola (By similarity).

Alternative names

• Flotillin-1
• FLOT1

Database links

• entrezGene:10211
• omim:606998
• swissprot:O75955

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

47355Da