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Function

Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

Cellular localization

  • Isoform 1
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform 2
  • Secreted

Alternative names

Fms-related tyrosine kinase 3 ligand, Flt3 ligand, Flt3L, SL cytokine, FLT3LG

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

26416Da

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