FYTTD1
Function
Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.
Sequence Similarities
Belongs to the UIF family.
Tissue Specificity
Expressed in a wide variety of cancer types.
Cellular localization
- Nucleus
- Nucleoplasm
- Nucleus speckle
Alternative names
UIF, FYTTD1, UAP56-interacting factor, Forty-two-three domain-containing protein 1, Protein 40-2-3