G-protein coupled receptor 20
Function
Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity
Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
G-protein coupled receptor 20, GPR20