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G0S2

Function

Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.

Tissue Specificity

Widely expressed with highest levels in peripheral blood, skeletal muscle and heart, followed by kidney and liver.

Cellular localization

Alternative names

G0/G1 switch protein 2, G0/G1 switch regulatory protein 2, Putative lymphocyte G0/G1 switch gene, G0S2

swissprot:P27469 entrezGene:50486 omim:614447