GA-binding protein subunit beta-1

Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:10675337, PubMed:8441384, PubMed:8816484). Acts as a master regulator of nuclear-encoded mitochondrial genes (By similarity).

(Microbial infection) Necessary for the expression of the Adenovirus E4 gene.

Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.

• Nucleus

E4TF1B, GABPB, GABPB2, GABPB1, GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB-2

• entrezGene:2553
• omim:600610
• swissprot:Q06547

Proteins

Oncology

42483Da