GABPB1
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats) (PubMed:10675337, PubMed:8441384, PubMed:8816484). Acts as a master regulator of nuclear-encoded mitochondrial genes (By similarity).
(Microbial infection) Necessary for the expression of the Adenovirus E4 gene.
Post-translational modifications
Acetylated by EP300/p300. Deacetylated by SIRT7, promoting heterotetramerization and activity.
Cellular localization
- Nucleus
Alternative names
E4TF1B, GABPB, GABPB2, GABPB1, GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB-2