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GADD45G
Domain
Two central helices mediate homodimerization through parallel packing.
Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Sequence similarities
Belongs to the GADD45 family.
Alternative names
- Growth arrest and DNA damage-inducible protein GADD45 gamma
- Cytokine-responsive protein CR6
- DNA damage-inducible transcript 2 protein
- DDIT-2
- GADD45G
- DDIT2
- CR6
Database links
Target type
Proteins
Molecular weight
17121Da