Growth arrest and DNA damage-inducible protein GADD45 gamma

Two central helices mediate homodimerization through parallel packing.

Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

Belongs to the GADD45 family.

CR6, DDIT2, GADD45G, Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2

• entrezGene:10912
• omim:604949
• swissprot:O95257

Proteins

Oncology

17121Da