GADD45G
Domain
Two central helices mediate homodimerization through parallel packing.
Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Sequence Similarities
Belongs to the GADD45 family.
Alternative names
CR6, DDIT2, GADD45G, Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2