GAL
Function
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
Involvement in disease
Epilepsy, familial temporal lobe, 8
ETL8
A focal form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe. Seizures are usually accompanied by sensory symptoms, most often auditory in nature.
None
The disease is caused by variants affecting the gene represented in this entry.
Sequence Similarities
Belongs to the galanin family.
Cellular localization
- Secreted
Alternative names
GAL1, GALN, GLNN, GAL, Galanin peptides