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Gc

Function

Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

Sequence Similarities

Belongs to the ALB/AFP/VDB family.

Cellular localization

Alternative names

Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, Gc

swissprot:P21614 entrezGene:14473