GCA
Function
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Tissue Specificity
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.
Cellular localization
- Cytoplasm
- Cytoplasmic granule membrane
- Peripheral membrane protein
- Cytoplasmic side
- Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Alternative names
GCL, GCA, Grancalcin