GCAT

Pyridoxal phosphate (PLP) dependent enzyme, which catalyzes the cleavage of 2-amino-3-oxobutanoate to glycine and acetyl-CoA.

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Strongly expressed in heart, brain, liver and pancreas. Also found in lung.

• Mitochondrion
• Nucleus
• Translocates to the nucleus upon cold and osmotic stress.

KBL, GCAT, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase

• entrezGene:23464
• omim:607422
• swissprot:O75600

Proteins

45285Da