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GCLM

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.

Sequence Similarities

Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.

Tissue Specificity

In all tissues examined. Highest levels in skeletal muscle.

Alternative names

GLCLR, GCLM, Glutamate--cysteine ligase regulatory subunit, GCS light chain, Gamma-ECS regulatory subunit, Gamma-glutamylcysteine synthetase regulatory subunit, Glutamate--cysteine ligase modifier subunit

swissprot:P48507 omim:601176 entrezGene:2730