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GCLM

Pathway

Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.

Sequence similarities

Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.

Tissue specificity

In all tissues examined. Highest levels in skeletal muscle.

Alternative names

  • Glutamate--cysteine ligase regulatory subunit
  • GCS light chain
  • Gamma-ECS regulatory subunit
  • Gamma-glutamylcysteine synthetase regulatory subunit
  • Glutamate--cysteine ligase modifier subunit
  • GCLM
  • GLCLR

Target type

Proteins

Molecular weight

30727Da