Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development.
Protein modification; protein glycosylation.
N-glycosylated.
Belongs to the glycosyltransferase 14 family.
Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced.
C2GnT-mucin type, C2GnT-M, hC2GnT-M, C2/4GnT, GCNT3
Proteins
Oncology
50864Da
We found 2 products in 2 categories
ab77728
ab160400