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GFAP
Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Post-translational modifications
Phosphorylated by PKN1.
Sequence similarities
Belongs to the intermediate filament family.
Tissue specificity
Brain; isoform 2 expressed at 20-fold lower level than isoform 1.
Cellular localization
- Cytoplasm
- Associated with intermediate filaments.
Alternative names
- Glial fibrillary acidic protein
- GFAP
- Gfap
Database links
Target type
Proteins
Primary research area
Neuroscience
Other research areas
- Cardiovascular
Molecular weight
49900Da