Gfap
Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Post-translational modifications
Phosphorylated by PKN1.
Sequence Similarities
Belongs to the intermediate filament family.
Tissue Specificity
Expressed in the cortex and hippocampus. Expression decreases following acute and chronic corticosterone treatment.
Cellular localization
- Cytoplasm
- Associated with intermediate filaments.
Alternative names
Glial fibrillary acidic protein, GFAP, Gfap