A2LD1

Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.

Belongs to the gamma-glutamylcyclotransferase family.

A2LD1, GGACT, Gamma-glutamylaminecyclotransferase, AIG2-like domain-containing protein 1, Gamma-glutamylamine cyclotransferase

• entrezGene:87769
• omim:613378
• swissprot:Q9BVM4

Proteins

Oncology

17329Da