GIGYF1
Domain
The GYF domain interacts with GRB10.
Function
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity).
Sequence Similarities
Belongs to the GIGYF family.
Alternative names
CDS2, PERQ1, PP3360, GIGYF1, GRB10-interacting GYF protein 1, PERQ amino acid-rich with GYF domain-containing protein 1