GIPR
Function
This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Post-translational modifications
N-glycosylation is required for cell surface expression and lengthens receptor half-life by preventing degradation in the ER.
Sequence Similarities
Belongs to the G-protein coupled receptor 2 family.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR