Gja5
Developmental stage
Expressed in arteries of the heart at 16.5 dpc (PubMed:28179430). Expressed in embryonic brain, skin, liver and kidney (PubMed:1318884).
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Sequence Similarities
Belongs to the connexin family. Alpha-type (group II) subfamily.
Tissue Specificity
Abundantly expressed in the lung, also expressed in the kidney and heart.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
- Cell junction
- Gap junction
Alternative names
Cxn-40, Gja5, Gap junction alpha-5 protein, Connexin-40, Cx40