GJD2
Function
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Sequence Similarities
Belongs to the connexin family. Delta-type subfamily.
Tissue Specificity
Highly expressed in neurons.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
- Cell junction
- Gap junction
Alternative names
GJA9, GJD2, Gap junction delta-2 protein, Connexin-36, Gap junction alpha-9 protein, Cx36