Gkn1
Function
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium.
Sequence Similarities
Belongs to the gastrokine family.
Tissue Specificity
Expressed in the stomach (PubMed:15221938). Highly expressed specifically in surface cells of the antrum mucosa from where it is secreted.
Cellular localization
- Secreted
- Cytoplasmic granule
- Golgi apparatus
- Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus.
Alternative names
Amp18, Ca11, Gkn1, Gastrokine-1, 18 kDa antrum mucosa protein, Protein CA11 homolog, AMP-18