GLUD2

Function

Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission.

Post-translational modifications

Stoichiometry shows that ADP-ribosylation occurs in one subunit per catalytically active homohexamer.

Sequence Similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Tissue Specificity

Expressed in retina, testis and, at a lower level, brain.

Cellular localization

• Mitochondrion matrix

Alternative names

GLUDP1, GLUD2, GDH 2

Database links

swissprot:P49448 omim:300144 genbank:NM_012084.3 swissprot:P00367 entrezGene:2747