Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2
Function
Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
Pathway
Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.
Tissue Specificity
Highest levels of expression in heart, placenta, and spinal cord.
Alternative names
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2, D-fructose-6-phosphate amidotransferase 2, Glutamine:fructose-6-phosphate amidotransferase 2, Hexosephosphate aminotransferase 2, GFAT 2, GFAT2, GFPT2