Glutaminyl-peptide cyclotransferase
Function
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue (By similarity).
Sequence Similarities
Belongs to the glutaminyl-peptide cyclotransferase family.
Cellular localization
- Secreted
Alternative names
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, QC, Qpct