Gnrh1
Function
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
Post-translational modifications
Gonadoliberin-1
The precursor is cleaved by ACE, which removes the Gly-Lys-Arg peptide at the C-terminus, leading to mature hormone. The mature form of Gonadoliberin-1 is also cleaved and degraded by ACE.
Sequence Similarities
Belongs to the GnRH family.
Cellular localization
- Secreted
Alternative names
Gnrh, Gnrh1, Progonadoliberin-1, Progonadoliberin I